Delayed Induction of Telomere Instability in Normal Human Fibroblast Cells by Ionizing Radiation
نویسندگان
چکیده
منابع مشابه
Delayed induction of telomere instability in normal human fibroblast cells by ionizing radiation.
We examined the delayed induction of telomere instability in hTERT-immortalized normal human fibroblast (BJ1-hTERT) cells exposed to X-rays. BJ1-hTERT cells were irradiated with 2 Gy of X-rays, and chromosome aberrations were analyzed 24 hours after irradiation and in the surviving cells 14 days after X-ray exposure. We found that the X-ray-surviving cells showed an increased frequency of chrom...
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All humans receive some radiation exposure and the risk for radiation-induced cancer at low doses is based on the assumption that there is a linear non-threshold relationship between dose and subsequent effect. Consequently, risk is extrapolated linearly from high radiation doses to very low doses. However, adaptive responses, bystander effects, and death-inducing effect may influence health ef...
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ژورنال
عنوان ژورنال: Journal of Radiation Research
سال: 2004
ISSN: 0449-3060
DOI: 10.1269/jrr.45.105